Yes, it is puzzling why Sibelius never turned to the quartet medium again, apart from the 'Andante Festivo' best known in its revised version for strings and timpani [JS 34b] but it was originally composed for string quartet in 1922 [JS 34a]
Sibelius's only mature quartet [Voces Intimae] was begun in 1908 and completed during his visit to London in march the following year. So it sits between the 3rd and 4th symphonies and around the time of the two Shakespeare songs and 'In memoriam'.
Ringbom tells us that Sib pencilled in the words 'Voces Intimae' over the three ppp chords of E minor at bar 21 in a copy of the score, at a point that displays a rapt, and withdrawn quality.
I feel that the first movement has distinct resemblances to the 6th symphony, both share the tonal centre of D minor [Dorian] and it has been pointed out that, as a structure it approaches the first movement of the 3rd symphony in perfection of form. In the second movement I always feel that the forest sprites are never far away and it builds up to a powerful climax. In the beautiful third movement 'Adagio di Molto' Sibelius seems to me to move ever closer to the Largo of the 4th symphony. After the Allegretto ma pesante, the Finale drives forward with tremendous momentum to its masterly conclusion.
I cannot agree with those who say that Sibelius thought in orchestral terms when he penned this masterpiece, it is as idiomatic as the quartets of Haydn.--kullervopete.